Preface

Basic biomedical research aims to provide a comprehensive and detailed under-

standing of the mechanisms that underlie the development and normal functions of

humans and other living organisms. Moreover, organismal physiology has been a

most significant challenge ahead in basic and clinical research. Attempts are on to

understand the integrated function of organs and organisms. Recently, researchers

have

facilitated

to

understand

the

disease-causing

pathological

and

phytophysiological mechanisms. There have been remarkable conceptual and tech-

nical advances in biological and biomedical sciences in the last few years and are

continuing rapidly. The genome project and developments of OMICS technologies

in combination with computational and imaging technologies have provided new

language to the understanding of occurrence, mechanism, and prevention of disease.

Now molecular mechanisms of many acquired and inheritable diseases have been

delineated. The mysteries of the brain are being unravelled for the study of cells,

organs, and patients. Though there has been an explosion of information in all these

areas, it is difficult to collate all that for practical uses. There is, thus, a wide gap in

knowledge and its applications. To mitigate the challenges faced by humans, this gap

must be bridged. There is a dire need to have an effective dialogue between

physicians and scientists. It will help in understanding clinical medicine in a much

practical way. The interaction of astute clinicians with patients may stimulate clinical

investigations that may suggest novel mechanisms of disease. There is, in fact, a

bidirectional flow of information from patients to the laboratory and back. It helps to

accelerate understanding of human diseases and develop new strategies to prevent,

diagnose, and treat them. Its route may pass through various experimentation and

validation stages in lower and higher animal species and now on chips, cell-free

systems, and bionomics. There can be no doubt that the frequency and intensity of

interactions have tremendously increased now. The primary and clinical workforces

linked by biomedical scientists are now also termed “translational” researchers. They

are trained to be knowledgeable in the primary and clinical biomedical sciences and

proficient in patient care.

The book Biomedical Translational Research is a platform for clinical

researchers, basic scientists, biomedical engineers, and computational biologists

from different countries to express their experiences and futuristic thoughts in the

form of chapters.

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